Early onset dementia

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Early-onset dementia.

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Early - Onset Dementia : a Multidisciplinary Pproach

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Meta-analysis of existing genome-wide association studies on Alzheimer's disease (AD) showed subgenome-wide association of an intronic variant in the sequestosome 1 (SQSTM1) gene with AD. We performed targeted resequencing of SQSTM1 in Flanders-Belgian AD patients selected to be enriched for a genetic background (n = 435) and geographically matched nonaffected individuals (n = 872) to investiga...

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ژورنال

عنوان ژورنال: Journal of the Neurological Sciences

سال: 2019

ISSN: 0022-510X

DOI: 10.1016/j.jns.2019.10.203